Application

Research Sub CategoryNeurofilament & Neuron Metabolism

Research CategoryNeuroscience

Western blot: 1:100-1:1,000
Immunocytochemistry: 1:100-1:1,000
Immunohistochemistry: 1:100-1:1,000
Optimal working dilutions must be determined by end user.

This Anti-MAP1LC3 C Antibody is validated for use in WB, IC, IH for the detection of MAP1LC3 C.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The human MAP1LC3 protein is homologous with the rat Map1LC3 and with yeast APG8. These proteins are likely to be involved in the formation of autophagosomal vacuoles (autophagosomes).

Immunogen

Synthetic peptide corresponding to a region within the N-terminus of human MAP1LC3 C protein.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Lyophilized. Reconstitute with 50 uL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Serum

Specificity

MAP1LC3 C [Microtubule-associated proteins 1A/1B light chain 3C, MAP1A/1B LC3 C, MAP1 LC3, LC3 C].

Storage and Stability

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.